`
New results from the PREDIMED study sugÂgest that a Mediterranean diet may improve heart failÂure bioÂmarkÂers, such as N‑terminal pro-brain natriÂuretic pepÂtide and oxiÂdized LDL, in high-risk indiÂvidÂuÂals. This findÂing could potenÂtially have a proÂtecÂtive effect on heart failÂure progÂnoÂsis and qualÂity of life for the milÂlions of peoÂple worldÂwide affected by the conÂdiÂtion.

New results from the PREDIMED study, the ongoÂing interÂvenÂtion study carÂried out by Spanish researchers, has found eviÂdence that a Mediterranean diet may improve cerÂtain meaÂsureÂments that are used to diagÂnose and proÂvide a progÂnoÂsis for heart failÂure.
Heart failÂure is a chronic conÂdiÂtion that is diagÂnosed when the heart musÂcle does not funcÂtion well, resultÂing in less pumpÂing of oxyÂgen-rich blood to the body. It can have sevÂeral causes. Treatment is based on conÂtrolÂling it with lifestyle changes and medÂicaÂtions, howÂever heart failÂure is a conÂdiÂtion that becomes worse as time goes by.
For this study the researchers wanted to examÂine if a Mediterranean diet can have a posÂiÂtive effect on heart failÂure bioÂmarkÂers as there was litÂtle data on the diet and these parÂticÂuÂlar indiÂcaÂtors.
The study, pubÂlished in the European Journal of Heart Failure, included 930 parÂticÂiÂpants who were at high carÂdioÂvasÂcuÂlar risk. They were assigned to either a low fat diet, as the conÂtrol diet, or to one of the Mediterranean diet variÂaÂtions supÂpleÂmented with either olive oil or nuts.
The results after one year showed sevÂeral changes in heart failÂure bioÂmarkÂers. Participants folÂlowÂing the Mediterranean diets showed a decrease in N‑terminal pro-brain natriÂuretic pepÂtide, which is a type of amino acid that is found in high levÂels in indiÂvidÂuÂals with heart failÂure and is usuÂally assoÂciÂated with a worse progÂnoÂsis. In addiÂtion, the Mediterranean diet groups also had lower levÂels of oxiÂdized LDL — parÂticÂuÂlarly in the olive oil group.
Heart failÂure affects over 23 milÂlion peoÂple worldÂwide and is charÂacÂterÂized by a decreased qualÂity of life. The researchers noted that their results show that the Mediterranean diet could modÂify these bioÂmarkÂers for a more proÂtecÂtive effect.