Spanish Researchers Begin Trialing Olive-Derived Treatment for Long Covid

A supplement made from polyphenols from olives and flavonoids from oranges will be given to patients to try and alleviate the symptoms associated with long Covid.
By David Uwakwe
Jun. 30, 2021 09:39 UTC

Spanish researchers have begun tri­al­ing a food sup­ple­ment made with polyphe­nols from olives and flavonoids from bit­ter oranges as a treat­ment for symp­toms of post-acute seque­lae SARS-CoV‑2 infec­tion, also known as long Covid.

The Endothelyx 45 sup­ple­ment will be given to patients who have passed the acute phase of the dis­ease but con­tinue to strug­gle with symp­toms such as chronic fatigue, joint pain and mem­ory loss.

The aim of the research is to study the effects of the sup­ple­ment on endothe­lial cells, which are found in the inner lin­ing of the arter­ies and play a key role in car­dio­vas­cu­lar health.

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It is thought that one of the ways in which Covid-19 attacks the body is by caus­ing inflam­ma­tion and oxida­tive stress in these cells result­ing in the symp­toms asso­ci­ated with long Covid.

Polyphenols are nat­ural bioac­tive com­pounds present in fruit, veg­eta­bles and other plants, which are known for their antiox­i­dant and anti-inflam­ma­tory prop­er­ties.

In recent years, they have been cred­ited with help­ing to pre­vent the devel­op­ment of cer­tain dis­eases, includ­ing can­cer, car­dio­vas­cu­lar dis­ease and neu­rode­gen­er­a­tive dis­eases.

In a sep­a­rate trial being car­ried out by the University Hospital of Jaén, another food sup­ple­ment con­tain­ing polyphe­nols from olives is being admin­is­tered to patients with mild or mod­er­ate Covid-19 symp­toms to study its effi­cacy in pre­vent­ing the ill­ness from pro­gress­ing to the acute stages.

According to a gov­ern­ment study from the United Kingdom, reported in the Guardian, more than two mil­lion adults in England have expe­ri­enced coro­n­avirus symp­toms last­ing for more than 12 weeks, twice as long as the pre­vi­ous esti­mate for long Covid.

The clin­i­cal trial, which is being car­ried out by the Regional University Hospital of Málaga, in col­lab­o­ra­tion with the Spanish com­pa­nies Genosa, Synlab and Solvitae Medical, will last for six months.


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