Research suggests that the Mediterranean diet’s benefit of lowering hepatic fat may be linked to the reduction of risk factors for chronic disease.
A study published in the Journal of Hepatology found that the Mediterranean diet was more effective than a low-fat diet in reducing hepatic fat, which is linked to serious diseases beyond liver health. The study involved 278 participants and showed that the Mediterranean diet led to a greater decrease in hepatic fat content and cardiovascular disease risk factors compared to a low-fat diet.
A study found the Mediterranean diet (MedDiet) was more effective than a low-fat diet in reducing hepatic fat (HF), which refers to liver fat.
Since elevated HF is linked to serious diseases, the discovery has implications for wellness that extend far beyond liver health.
(The) Mediterranean/low-carbohydrate diet induced a greater decrease in hepatic fat content than low-fat diet, and the beneficial health effects were beyond the favorable effects of visceral fat loss.- researchers on the study
The study, published in the Journal of Hepatology, examined whether losses in HF related to dietary interventions were linked to losses in visceral fat, known as abdominal or belly fat.
It involved 278 participants of an average age of 48 with visceral fat and elevated lipids in the blood. The individuals were randomly assigned either a MedDiet or a low-fat diet with and without exercise for 18 months. Visceral fat was measured using magnetic resonance imaging.
See Also:Health NewsAfter six and 18 months, both dietary groups had a reduction in HF, which was tied to a lowering of visceral fat that surpassed what would be expected due to weight loss. Moreover, the MedDiet was associated with a significantly greater decrease in HF and cardiovascular disease risk factors.
“High hepatic fat content is associated with metabolic syndrome, type two diabetes mellitus, and coronary heart disease,” the researchers wrote. “In this 18-month intervention trial, Mediterranean/low-carbohydrate diet induced a greater decrease in hepatic fat content than low-fat diet, and the beneficial health effects were beyond the favorable effects of visceral fat loss.”
Gynecologist and fertility physician Tina Koopersmith of West Coast Women’s Reproductive Center in Sherman Oaks, California, did not participate in the study, but told Olive Oil Times that the findings make sense to her since Mediterranean diet is not only low in fat, but also full of important nutrients.
“The MedDiet differs from the low-fat diet in various ways,” she said. “It’s much richer in healthy monounsaturated fats, which are present in extra virgin olive oil, avocados and nuts. In addition, it contains less sugar and refined grains than a standard low-fat diet.”
“HF is often seen with dysmetabolic syndrome, a condition of insulin resistance, elevated blood pressure and pre-diabetes,” she added. “Fat in this area is also an indicator or risk factor for cardio-metabolic disorders such as diabetes and heart disease.”
“Results from the study suggest a reversal or improvement in some of the underlying etiologies of today’s common diseases,” she continued. “For years, we have been told that we should avoid all fat in the diet because of the link between HF and certain disorders, as well as the association between atherosclerotic plaque and heart disease. However, people in France and in countries that border the Mediterranean Sea don’t avoid fat in the diet, yet they don’t have the incidence of chronic disease that we see in the United States.”
“In recent years, scientists looking more deeply into the MedDiet have found that its high content of healthy monounsaturated fats and avoidance of refined carbohydrates seem to be associated with better outcomes,” she concluded. “Research also shows that the MedDiet is linked to lower insulin resistance and less deposition of fat in the liver. These effects lead to a better functioning liver with less inflammation in the body, thus translating to better health.”
More articles on: Mediterranean diet, health, olive oil health
Jun. 28, 2025
Oleacein: The Promising Phenolic Compound in Extra Virgin Olive Oil
Oleacein, a phenolic compound found in extra virgin olive oil, has antioxidant, anti-inflammatory, and potential anti-atherosclerotic properties with significant impacts on human health.
Sep. 25, 2025
MedDiet Adherence May Protect Against Gum Disease
New research shows that the anti-inflammatory foods in the Mediterranean diet may prevent periodontal inflammation. Oleic acid may also protect oral health compared to other dietary fats.
Jan. 9, 2025
MedDiet Named World’s Best for Eighth Straight Year
A panel of experts selected the Mediterranean diet as the world’s best due to its variety of nutrient-dense foods, health benefits and flexibility.
Oct. 1, 2025
Swiss Psychiatric Hospital Adopts Olive Oil for Patient Health
Extra virgin olive oil is replacing other fats in the PDAG in Switzerland, in a decision driven by scientific evidence.
Apr. 29, 2025
Study Confirms Olive Oil's Role in Weight Management
A review of 121,119 participants in the Nurses' Health Study found that consuming olive oil is associated with reduced weight gain over time.
Nov. 4, 2025
Frequent Olive Oil Consumption Linked to Smaller Waistlines, Study Finds
People who consume extra virgin olive oil nearly every day tend to have smaller waistlines, according to a new study examining the dietary habits of more than 16,000 adults.
Jun. 11, 2025
EFSA Panel Rejects Some Olive Oil Polyphenol Health Claims
The panel rejected two submissions from Italy and Spain, stating that the scientific evidence fell short of the requirements.
Jul. 17, 2025
New Research Shows Olive Oil's Impact on Gut Health
The research review revealed the powerful impact of extra virgin olive oil on gut health, immune function, and overall well-being through its bioactive compounds.